Medicines that influence liver metabolism may result in elevated blood amounts of codeine. Never give along with expectorants, Because the additional reproduced mucus can not be coughed off because of the antitussive influence of dihydrocodeine.
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Codeine is contraindicated in patients with recognised or suspected gastrointestinal obstruction, which includes paralytic ileus; the usage of codeine may well obscure the analysis or scientific program of sufferers with acute abdominal conditions; the concurrent utilization of website anticholinergics may produce paralytic ileus
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This decision don't just addresses issues concerning the misuse and addictive likely of codeine linctus but will also underscores the importance of prioritising affected individual read more nicely-getting.
Medication which have restrictions other than prior authorization, amount boundaries, and stage therapy linked to Every single prescription.
For anyone who is employing sustained-launch tablets or capsules, swallow the medication total. Tend not to crush, chew, or split the tablets or capsules. Doing so can damage the very long action from the drug and could enhance Unintended effects.
No major conversation is predicted with concurrent usage of opioid analgesics and alvimopan in people who been given opioid analgesics for seven or much less consecutive times ahead of alvimopan.